Session 991: Molecular Pathology

Cochair(s): VE Valli, P Camilleri
Date: Sat 9 February 2002, Time: 11:30 - 13:00
Location: CIS Auditorium

Oral Presentations

Time Number Title / Authors / Affiliations
11:30 1 The influence in BRCA1/2 mutation carriers of the specific histologic features of their breast cancers on the mammographic images.
MMA Tilanus-Linthorst, LC Verhoog, AI Obdeijn, M Heiboer, JGM Klijn, AM Eggermont, CTM Brekelmans, T van der Kwast
1Department of Surgery, 2Department of Pathology, 3Department of Radiology, 4Department of Medical Oncology, 5Department of Genetics; Erasmus Medical Centre, Rotterdam, Netherlands
11:45 2 The impact of BRCA1 and BRCA2 testing on surgical decision-making
E Matloff
Yale Cancer Center/Yale School of Medicine, New Haven, CT United States
12:00 3 A preliminary study of surgical margins with P53, B72.3 and HER-2/neu to evaluate the molecular basis for tumor field.
GAP Ganepola, A Gritsman, A Yiengpruksawan, L Rizzo, R Vurtser
1Columbia University Medical Center, New York, NY, 2Cancer Institute, The Valley Hospital, Ridgewood, NJ
12:15 4 The use of soluble salivary c-erbB-2 to detect breast cancer in women: a five year study.
C Streckfus, L Bigler, L Copeland
Office of Research, University of Mississippi Medical Center, Jackson, MS
12:30 5 Role of P-cadherin in the pathogenesis of mammary Paget disease
AC Han
The Reading Hospital Regional Cancer Center, West Reading, PA
12:45 6 Simultaneous methylation of the E-cadherin and p16 gene promoter in breast cancer.
VH Deshmane, IS Fentiman, IR Hart
1Department of Surgical Oncolgy Hinduja Hospital, Mumbai, India, 2Breast Unit, Guy's Hospital, London, UK, 3Richard Dimbleby Department of Cancer Research/ICRF Lab, St Thomas' Hospital, London, UK
13:00 7 Transforming growth factor-beta regulates the expression of E-cadherin through extracellular matrix remodeling and focal adhesion kinase.
S Chakrabarty
University of Texas, M.D. Anderson Cancer Center, Houston, Texas United States

Poster Presentations

Number Title / Authors / Affiliations
8 Revealing predictors of disease susceptibility in dysplastic ulcerative colitis using oligonucleotide array technology
SMS Uthoff, NPS Crawford, W Zacharias, MR Eichenberger, H-P Bruch, S Galandiuk
1Digestive Surgery Research Laboratory, Department of Surgery, University of Louisville School of Medicine, Louisville, KY, 2Surgical Research Laboratory, Surgical Clinic, Luebeck, Germany, 3Department of Medicine and Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY
9 Human sequences closely related to the gene env of MMTV, in peripheral blood mononuclear cells of breast cancer patients.
P Makhov, A Lushnikova, T Malivanova, N Karmosh, A Denisova, K Laktionov, E Polevaya, I Kryukova
1Institute of Carcinogenesis CRC RAMS, , 2Institute of Clinical Oncology1 CRC RAMS
10 Expression of high molecular weight cysteine proteinase inhibitor in ovarian cancer tissues and regulation of cathepsin B expression by placental CPI.
Y Saleh, M Siewinski, A Popiela, P Ziólkowski, M Jelen, J Rybka
1Department of Pathology, Medical University of Wroclaw, Wroclaw, Poland, 2Department of Obstetrics and Gyneacology Medical University of Wroclaw, Polish Academy of Sciences, 12 Weigla St, 3Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla St, 53 -114 Wroclaw
11 Autocrine stimulation of human pancreatic duct-like development by soluble isoforms of epimorphin in vitro
L Lehnert, MM Lerch, Y Hirai, M Kruse, H Kalthoff
1Molecular Oncology, Department of General and Thoracic Surgery, 4First Department of Medicine, Laboratory for Molecular Gastroenterology and Hepatology; Christian-Albrechts-University, Kiel, Germany, 2Department of Medicine B, Westfälische Wilhelms-University, Münster, Germany, 3Sumitomo Industries, Yokohama, Japan, 5Medical Clinic, Knappschaftskrankenhaus, Germany
12 p53 in nonneoplastic CNS lesions: an immunohistochemical and gene sequencing study
Ö Kurtkaya-Yapicier, BW Scheithauer, CD James
1Marmara University, Istanbul, Turkey, 2Mayo Clinic, Rochester, MN
13 Histologic-genetic mapping of cystectomy specimens in bladder cancer patients reveals frequent genetic alterations in dysplastic and histologically normal urothelium
R Stoehr, R Knuechel-Clarke, R Schmitt, F Hofstaedter, A Hartmann
1Institute of Pathology, 2Department of Genetics; University of Regensburg, Germany
14 K-ras mutations in colorectal polyps: site, histology and size do matter.
GL Williams, GJS Jenkins, J Beynon, JM Parry
1Department of Surgery, Singleton Hospital, Swansea, UK, 2School of Biological Sciences, Swansea University, Swansea, UK
15 Molecular analysis of tumors related with Multiple Endocrine Neoplasia type 1. Microsatellite instability: a frequent event in insulinomas
A Cebrián, S Ruiz-Llorente, A Cascon, D Telleria, J Benitez, M Robledo
Centro Nacional de Investigaciones Oncologicas Carlos III, Majadahonda, Madrid Spain
16 Helicobacter pylori infection and host immunity in patients with MALT lymphoma.
K Yokota, S Hayashi, H Mano, Y Hirai, K Oguma
1Okayama University Graduate School of Dentistry and Medicine, Okayama, Okayama Japan, 2Jichi Medical School, Yakushiji, Tochigi, Japan
17 Characterization of tumor-associated antigens in colon cancer
A Line, Z Slucka, A Stengrevics, K Silina, G Li, E Jankevics, RC Rees
1Biomedical Research and Study Centre, University of Latvia, Riga, Latvia, 2Latvian Oncology Center, Riga, Latvia, 3Department of Life Sciences, Nottingham Trent University, Nottingham, UK
18 Phenotypic modulation of smooth muscle cells through EGF family ligand- and EGFR-triggered signaling pathways
Y Yamanaka, K Hayashi, T Komurasaki, S Morimoto, K Sobue
1Department of Neuroscience, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, 22-2 Yamadaoka, Suita, Osaka, Japan, 3Research Center, Taisho Pharmaceutical Co. Ltd, Yoshino-cho, Omiya
19 HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway
Y Wen, M Hu, K Makino, W Spohn, G Bartholomeusz, D Yan, MC Hung
the University of Texas, M. D. Anderson Cancer Center, Houston, Texas United States
20 Choline kinase activity in cancer and normal human mammary epithelial cells.
G Eliyahu, E Rushkin, H Degani
Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel
21 Partial restoration of degraded DNA from archival paraffin embedded tissues
EN Imyanitov, MY Grigoriev, VM Gorodinskaya, ES Kuligina, KM Pozharisski, AV Togo, KP Hanson
N.N. Petrov Institute of Oncology, Russia
22 Profiling of integrin α3 β1 N-linked oligosaccharides using DNA-sequencer.
A Litynska, P Laidler, E Pochec, N Callewaert, R Contreras
1Institute of Zoology, Jagiellonian University, Kraków, Poland, 2Institute of Medical Biochemistry, Medical College, Jagiellonian University, Kraków, Poland, 3Department of Molecular Biology, Ghent University and Flanders Interuniversity Institute for Biotechnology, Belgium
23 LPS-Induced TNF-Alpha Factor (LITAF) is a transcriptional target of p53 – New evidences for a role of p53 in inflammatory diseases.
S Amar, A Bolcato-Bellemin
Boston University Medical Center, Boston, USA
24 Fluctuation of endogenous TNF alpha concentration in plasma in advanced cancer patients
M Muc-Wierzgon, A Sterno, J Wierzgon, B Zubelewicz, T Kokot, E Nowakowska
15th Department of Internal Diseases, Silesian Medical University, Bytom, Poland, 2Department of Surgery, Centre of Oncology, M. Curie-Sklodowska Memorial Institute, Branch Gliwice, Poland
25 Analysis of telomerase activity and expression and telomere length in leukemic cells
D Januszkiewicz, K Lewandowski, K Nowicka-Kujawska, M Pernak, J Rembowska, W Cichy, J Nowak
Institute of Human Genetics Polish Academy of Sciences, Institute of Pediatrics Academy of Medical Sciences, Department of Medical Diagnostics Poznan, Poland
26 The role of steroid metabolism in women with breast cancer in different menopausal status. Comprehensive study.
V Poór, S Juricskay
Central Research Laboratory, Faculty of Medicine, University of Pécs, Hungary
27 LDH release from K-562 cells after TNF-α treatment
J Vladimir, B Banicevic, G Konjevic, I Spuzic
1School of Medicine University of Kragujevac, Belgrade, Serbia, 2Institiuute of Haematology Belgrade, Belgrade, Serbia, 3Institute of Oncology and Radiology, Belgrade, Serbia, Yugoslavia
28 Co-compartmentalisation of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.
DP Xirodimas, S David, P Lane
Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK. [ok]
29 Radiobiological characteristics of solid tumors depending on the p53 status of the tumor cells -- reference to the response of intratumor quiescent cells
S Masunaga, A Takahashi, T Ohnishi, M Takagaki, Y Kinashi, K Ono
1Research Reactor Institute, Kyoto University, Kumatori, Sennan-gun, Osaka Japan, 2Department of Biology, Nara Medical University, Kashihara, Nara, Japan, 3Department of Neurosurgery, Aino Junior College Hospital, Ibaraki, Osaka, Japan
30 Large Granular Lymphocyte (LGL) disorders: A comparative study of T vs Natural Killer (NK) variants
MA Neben, WG Morice, PJ Kurtin, CA Hanson, RL Phyliky, A Tefferi
1Mayo Medical School, Rochester, MN United States, 2Division of Hematopathology, Mayo Clinic, Rochester, MN, 3Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN
31 Dendritic cell histiocytoma of the spine in a pediatric patient: case report
VM Morreale, AN Lorenzana, H Sawaf, MJ Higgins, H David, P Chuba
St. John Hospital and Medical Center, Detroit, Michigan United States
32 Syk-kinase protects Lyn-kinase from ubiquitination
B Dean, D Metcalfe
1Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD 20892, 2Center for Biologics and Evaluation Research, 3Food and Drug Administration, Bethesda, MD 20892
33 Molecular and immunological approach to hematological disease: detection and analysis of intracellular modified nucleosides by flowcytometory
I Honda, K Itou, M Mizugaki, T Sasakati
1National Iwate Hospital, , 2Tohoku University School of Medicine