Session 1195: Novel Therapies, Part 1
Cochair(s): J Shay,
Date: Mon 11 February 2002,
Time: 14:00 - 16:00
Location: Amphithéâtre Duclaux
Oral Presentations
| Time |
Number |
Title / Authors / Affiliations |
| 14:00 |
456 |
Lymphoma
growth-inhibitory activity of sulfasalazine (SASP)
involves inhibition of cysteine supply by somatic
cells.
PW Gout, MC Robertson
BC Cancer Agency,
Vancouver, Canada |
| 14:15 |
457 |
Natural human
antibody and intravenous immunoglobulin regulation of T
cell activation
DA Chow, Y Li, S Hebert
University of Manitoba,
Winnipeg, Canada |
| 14:30 |
458 |
Modulation of
Calcium-activated K-channels in T cells: A novel
therapeutic approach?
LS Madsen, M Hertz, D Strøbæk, P Christophersen, FA Sløk,
A Gautam, PhD Jensen
1Section of
Ion channel Pharmacology, NeuroSearch A/S, Ballerup,
Denmark, 2Poseidon Pharmaceuticals, Ballerup,
Denmark, 3Pharmexa A/S, Hørsholm,
Denmark |
| 14:45 |
459 |
Control of cell
proliferation via redox-regulated expression of
glycolytic genes
KA Brand, U Aulwurm, D Fabian, B Hamm-Kuenzelmann, R
Netzker, D Schaefer, C Weigert
University
Erlangen-Nuremberg Medical Faculty, Erlangen, Bavaria
Germany |
| 15:00 |
460 |
Pharmacological
perspectives of mistletoe therapy
T Hajto
Hungarian Immune Therapy
Health and Service Deposit Partnership, Budapest,
Hungary |
| 15:15 |
461 |
Chemoprevention
of chemically-induced intestinal carcinoma in rats by
combined octreotide, galanin and serotonin treatment and
by cyclooxygenese-2 inhibitor
ME El-Salhy
Public Health and
clinical Medicine, Umeå, Sweden |
| 15:30 |
462 |
Which dosing
scheme is suitable for the taxanes? An in vitro
model
UA Sanli, R Uslu, B Karabulut, VC Sezgin, G Saydam, SB
Omay, F Buyukkececi, E Goker
Department of
Hematology-Oncology Ege University Medical School,
Bornova-Izmir, Izmir Turkey |
| 15:45 |
463 |
Radiation induced
shedding of TGF alpha results in a prolonged period of
refractoriness to further release of TGF
alpha
MP Hagan, A Yacoub
Medical College of
Virginia, Richmond, Virgina United States |
Poster Presentations
| Number |
Title / Authors / Affiliations |
| 464 |
The effect of
retinoic acid on sodium-iodide symporter gene (NIS)
expression in breast cancer and normal breast
cells
M Jarzab, V Piddubnyak, J Szary, B Maka, M Wiench, B
Nikiel, A Goraj-Zajac, K Lisowska, Z Krawczyk
1Dept. of
Tumor Biology, Molecular Biology, , 2Dept. of
Tumor Biology, Surgery, , 3Dept. of Tumor
Biology, Nuclear Medicine and Endocrine Oncology, ,
4Dept. of Tumor Biology, Pathology, ,
5Dept. of Tumor Biology, Centre of Oncology --
Maria Sklodowska-Curie Memorial Institute, Gliwice
Branch, Poland |
| 465 |
*The tyrosine
kinase inhibitor sti571 downregulates gene expression by
reducing histone h4 acetylation and histone deacetylase
(hdac) expression.
G Brusa, C Santucci, L Pattacini, M Mancini, L
Mazzacurati, M Baccarani
University of Bologna
Medical School, Bologna, Bologna Italy |
| 466 |
Rapamycin
prevents calcineurin inhibitor-associated tumor
progression
M Hojo, F Luan, M Maluccio, K Yamaji, M
Suthanthiran
Division of
Nephrology/Transplantation Medicine New York Presbyterian
Hospital/Weill Medical College of Cornell University, New
York, NY USA |
| 467 |
The effect of
cisplatin and docetaxel on p53 and mdm2 in cancer cell
lines
L Laatio, R Serpi, U Puistola, K Vahakangas
1Department
of Pharmacology and Toxicology, University of Oulu, Oulu,
Finland, 2Department of Obstetrics and
Gynecology, University Hospital of Oulu, Oulu, Finland,
3Department of Pharmacology and Toxicology,
University of Kuopio, Kuopio, Finland |
| 468 |
Possible
cytotoxic effects of lipophilic o-naphthoquinones in
isolated rat hepatocytes; protective
mechanisms.
M Dubin, F Villamil, NV De Witte, PH Carrizo, M Portela,
AOM Stoppani
School of Medicine,
Bioenergetics Research Centre, University of Buenos
Aires, Argentina |
| 469 |
*Prevention of
radiation-induced pulmonary fibrosis by blockade of
transforming growth factor-beta (TGF-β)
signaling
A Nishioka, Y Ogawa, S Kariya, S Yoshida, H Ueno
1Department
of Radiology, Kochi Medical School, Nankoku, kochi Japan,
2Department of Biochemistry and Molecular
Pathophysiology, School of Medicine, University of
Occupational and Environmental Health, Kitakyusyu,
Fukuoka Japan |
| 470 |
Peroxisome
proliferators as differentiating agents: an intriguing
mechanism of action.
R Scatena, G Nocca, P Bottoni, I Messana, F Vincenzoni, L
Ceccarelli, B Giardina
Institute of
Biochemistry and Clinical Biochemistry. Catholic
University, Largo A. Gemelli, 00168- Rome,
Italy |
| 471 |
The
radiosensitizing effect of Pentoxifylline at high dose
rate compared to low dose rate
irradiation.
A Danielsson, E Karlsson, C Mercke
Department of Oncology,
Goteborg University, Sweden |
| 472 |
In vivo
genotoxkinetics: an alternative to study pharmacokinetics
and pharmacodynamics of antineoplastic agent
busulfan
P Morales-Ramirez
Instituto Nacional de
Investigaciones Nucleares, Mexico D.F, Mexico |
| 473 |
Effects of
ganglioside biosynthesis inhibition on the expression and
phosphorylation of the membrane tyrosine-kinase receptors
p185neu/ErbB2 in tumor and normal mammary cell
lines.
E Sottocornola, I Colombo, B Berra
Institute of General
Physiology and Biological Chemistry, School of Pharmacy -
University of Milan, Milan, Italy |
| 474 |
Parathyroid
carcinoma: twenty cases. Up to date in a high rate
incidence series
SMM Basso, F Lumachi, R Behboo, G Favia
Endocrine Surgery Unit.
Department of Surgical and Gastroenterological Sciences.
University of Padova. Italy |
| 475 |
Radiopharmaceutical
and pharmaceuticals for the cure of prostate
cancer
S Shukla, D Sc, R Cusumano, G Atzei, G Argirò, S Boemi, G
Politano, P Iannantuono, C Cipriani, F Petrucci, A
Alimonti, S Caroli, M Sinibaldi
1Department
of Nuclear Medicine, Ospedale S. Eugenio, Roma, Roma
Italy, 2Institute of Chromatography CNR Roma,
Roma Italy, , 3Department of Urology, Aurelia
Hospital, Roma Italy, , 4Laboratory of Applied
Toxicology, Rma Italy |
| 476 |
Influence of
various administration routes on the antitumor activity
of a somatostatin analog, TT-232
M Tejeda, D Gaál, G Kéri
1National
Institute of Oncology, Budapest, Hungary,
2Institute of Biochemistry, Semmelweis
Uni.Med.Sch, Budapest, Hungary |
| 477 |
*Novel Drug
Resistance-associated Protein and new plant derived
modulators for overcoming drug resistance in human tumor
cells
C Ramachandran, SJ Melnick, T Rabi, E Escalon
Research Institute,
Miami Children's Hospital, Miami, FL 33155 |
| 478 |
Germline mutation
screening of DNA repair genes MLH3 and MBD4 in typical
and incomplete HNPCC families
Q Wang, G Montmain, C Lasset, V Bonadona, F Desseigne, JC
Saurin, A Puisieux
1Centre Leon
Berard, Lyon, France, 2Hopital Edouard
Herriot, Lyon, France |
| 479 |
Microphysiological
testing for chemosensitivity of tumor cells with
multiparametric microsensor-chips
AM Otto, M Brischwein, H Grothe, EM Motrescu, B
Wolf
Technical University of
Munich, Munich, Germany |
| 480 |
EWS-FLI1 targeted
vectorized antisense oligonucleotides inhibit a model of
Ewing sarcoma in mice
A Maksimenko, G Lambert, JR Bertrand, E Fattal, F Subra,
H Pinto-Alphandary, C Malvy, C Auclair, P Couvreur
1Laboratoire
de physico-chimie, pharmacotechnie et biopharmacie,
Faculté de Pharmacie, Chatenay Malabry,
2Laboratoire de physico-chimie et
pharmacologie des macromolécules biologiques, Institut G.
Roussy, Villejuif, France, 3Bioalliance Pharma
SA, Boulevard du Général Martial Valin, 75015 |
| 481 |
Effects of serine
protease inhibitor 4-(2-aminoethyl)benzenesulfonyl
fluoride (AEBSF) on the blood-brain barrier (BBB)
functions of cultured cerebral microvascular endothelial
cells (CMEC)
P Megyeri, MD Deli, H Takahata, M Niwa, KM Pabst, MJ
Pabst, CS Ábrahám
1Department
of Pediatrics and Infectious Diseases, Albert
Szent-Györgyi School of Medicine, University of Szeged,
Szeged, Hungary, 2Laboratory of Molecular
Neurobiology, Institute of Biophysics, Biological
Research Center, Hungarian Academy of Sciences, Szeged,
Hungary, 3Department of Pharmacology, Nagasaki
University School of Medicine, Nagasaki, Japan,
4Dental Research Center and Department of
Biochemistry, University of Tennessee, Memphis, TN
USA |
| 482 |
Docetaxel in the
treatment of advanced breast cancer
E Salminen
Department of
Radiotherapy and Oncology, Turku University, Turku,
Finland |
| 483 |
Serum her-2 ecd
and it's evolving role in management of breast cancer
patients
A Voss, R Neumann
Bayer Vital GmbH,
Leverkusen, Germany |
| 484 |
Primary gastric
lymphoma: a retrospective study
A Zeidman, E Ramadan, Z Fradin, Z Dreznik, M
Mittelman
Rabin Medical Center,
Hasharon Hospital, Petah-Tikva, Israel |
| 485 |
The combination
of APO2L/TRAIL with protein synthesis inhibitors or
tyrosine kinase inhibitors inhibits pancreatic cancer
growth in vitro and in vivo
J Standop, F Nozawa, M Schneider, RE Brand, XZ Ding, A
Ulrich, K Picha, TE Adrian, PM Pour
1UNMC Eppley
Institute, Department of Gastroenterology, and, Omaha,
NE, 2Creighton University, Omaha, NE,
3Immunex Corp, Seattle, WA |
| 486 |
Effects of
roscovitine on DNA synthesis in normal and neoplastic
glial cells.
MF Vita, JS Yakisich, J Boethius, O Lindblom, L
Wallstedt, I Vargas, A Sidacon, M Cruz
Karolinska Institute,
Stockholm, Stockholm, Sweden |
| 487 |
Glycoglycerolipid
analogues active in cancer chemoprevention: the role of
the ester function on the inhibition of Epstein-Barr
virus early antigen activation
F Ronchetti, D Colombo, F Compostella, A Scala, H Tokuda,
H Nishino
1Department
of Chemistry and Medical Biochemistry, University of
Milan, Milan, Kyoto 602-0841, 2Kyoto
Prefectural University of Medicine, Kamigyo-ku, Kyoto
602-0841, 3Department of Biochemistry, Kyoto
Prefectural University of Medicine, Kamigyo-ku, Kyoto,
Japan. fiamma.ronchetti@unimi.it |
| 488 |
Regulation of
proliferation/apoptosis equilibrium by map kinases in
normal, hyperplastic and carcinomatous human
prostate
M Royuela, MI Arenas, M Ricote, J Alfaro, MVT Lobo, R
Vera, B Fraile, R Paniagua
University of Alcala,
Alcala de Henares, Madrid Spain |
|
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