Multidrug Resistance - MDR
The lambda-Int family recombinases, Cre and Flp are inhibited by topoisomerase I targeting anticancer drugs
Molecular basis of the ability of new antitumour agents - benzoperimidines and anthrapyridones - to overcome multidrug resistance.
The cyclosporin PSC 833 prolongs survival of NOD-SCID mice following xenotransplantation with human myeloblasts carrying P-glycoprotein
Evaluation of multidrug resistance in in vitro treated cells of cancerous patients versus healthy donors by single cell gel electrophoresis assay (SCGE) assay.
The activity of latent benzoperimidine esters to inhibit P-glycoprotein and MRP1 dependent efflux of pirarubicin from several lines of multidrug resistant tumour cells.