ISPO

Familial Predisposition

Presymptomatic detection and treatment of gene carriers of multiple endocrine neoplasia families by screening for germ-line mutations of the ret gene

S Uchino MD, S Noguchi MD, M Adachi MT, M Sato MT, N Murakami MD, H Yamashita MD, S Watanabe MD, M Toda MD

Aniridia, PAX6 gene, WAGR syndrome and the risk of neoplastic proliferation

I Ivanov MD, A Shuper MD, M Shohad MD, M Snir MD, R Weitz MD

Mutation of the ret proto-oncogene in sporadic medullary thyroid carcinoma

M Kaun MD, M Bockhorn, C Franz MD, W Hoppner MD, A Frilling MD, C Broelsch MD

BRCA 1 LOH in early-onset and familial breast cancer

P Querzoli MD, R Rinaldi MD, G Albonico MD, S Ferretti MD, A Rasi MD, M Matteuzzi BS, E Magri HT, I Nenci MD

Haplotype analysis, a strategy to locate prevalent mutations, with an application to hereditary breast-ovarian cancer

A Dorum, P Moller, E-J Kamsteeg, H Scheffer, M Burton, KR Heimdal, LO Muhle, E Hovig, CG Trope, A van der Hout, M van der Meulen, C Buys,G te Meerman

Early detection of breast cancer by [16 alpha-iodine I-123] iodo-estradiol 17 beta and SPECT imaging

D Preston MD, J Spicer MS, R Baranczuk PhD, M Schiefelbein CNMT, K Baxter MD, M Redick MD PhD

Eficiency of clinical survey of women with a high genetic risk of breast cancer, ovarian carcinoma and cancer of endometrium

K Jordania MD, L Akulenko MD, S Nikogosyan MD, T Chimitdordjieva MD

Cytogenetic study of a family with high predisposition to stomach cancer

A Monakhov PhD, A Gulyaev MD, I Savochkina, S Fedorov MD PhD

Specific cloning of DNA fragments from the DNA of a patient with an 21 chromosome amplification in high-risk stomach cancer family

S Fedorov MD, E Belogubova, A Gulyaev MD, A Monachov PhD,

FAP: clues to the function of APC protein by unraveling genoptype-phenotype correlations

R Caspari MD, W Friedl MD, P Propping MD

Molecular analysis of 25 hereditary nonpolyposis colon cancer (HNPCC) families

J Buerstedde MD, Y Maliaka MD, R Scott PhD, P Hutter PhD, H Muller MD, N Bochkov MD

HNPCC families with mutations in DNA mismatch repair genes have a mean age of onset of colorectal cancers significantly lower than HNPCC families without mutation

P Radice PhD, V Pensotti PhD, S Presciuttini PhD, D Calistri PhD, I Gazzoli PhD, AP Grimalt Perez PhD, P Mondini BCS, P Sala PhD, C Rossetti MD, G Buonsanti PhD, NG Ranzi PhD, L Barratry MD, MA Puerto PhD

Germline HMLH1 and HMSH2 mutations predisposing to the development of colorectal carcinoma

M Genuardi , A Viel , F Leonardi , A Bellacosa , E Capozzi , M Anti , M Ponz de Leon , M Boiocchi , G Neri ,

Mutations of retroviral sequences in family members of adult T cell leukemia patients

K Maruyama MD PhD, M Miyauchi PhD, S Mochizuki PhD, N Koshikawa BS, K Kawamura MD, M Nakano MD PhD

Hereditary non-polyposis colorectal cancer: who and how shall be screened?

R Caspari MD, C Lamberti MD, R Kruse MD, W Friedl MD, P Propping MD, T Sauerbruch MD